Newly discovered cannabinoids show promise for medical pain applications

06 September 2022

1 minute read

Source/Disclosures

Source:

Jacknin J. How Green Is My Valley: Newly Discovered Cannabinoids and Their Possible Medical Uses. Featured at: PAINWeek; Vegas; September 6-9, 2022.

Disclosures:
Jacknin claims to be CEO of Dr. Jacknin’s Skincare LLC. It does not report any other relevant financial information.


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LAS VEGAS – Lesser-known cannabinoids show potential for treating neurological disease, inflammation, pain, cancer and infection, dermatologist says Jeannette jackinMD.

Jacknin, CEO of Dr. Jacknin’s Skincare in Encinitas, Calif., spoke at PAINWeek 2022 about the potential benefits of newly discovered cannabinoids, including cannabigerol acid (CBGa), cannabinol (CBN), cannabichromene (CBC), and tetrahydrocannabinolic acid (THCa).

“Of the approximately 113 cannabinoids, the most common being CBD, less than 10% have been researched,” Jacknin told participants.

CBGa has recently been shown to be useful in the treatment of neuropathic pain, neurodegenerative diseases, epilepsy, cancer and skin disorders, she said.

According to Jacknin, research involving CBN has revealed its anti-inflammatory properties, effectiveness in lowering intraocular pressure, neuroprotection, helpful effects in ADHD and pain control, appetite stimulation, and antibacterial properties. .

CBC is also important in neurology, she noted, and studies have shown that CBC improves neural stem progenitor cell function. “It encourages neurogenesis,” Jacknin said. “We can only think it would be useful as we get older.”

This cannabinoid also protects against oxidative stress, which can contribute to neurological conditions such as Alzheimer’s disease and dementia, Jacknin said. It works best for depression when combined with THC and CBD, and may also be useful for pain and acne relief and as an antibacterial, she continued.

Clinical trials need to be done at different levels, Jacknin said, “but it’s amazing for the future.”

According to Jacknin, the neuroprotective effects of THCa can apply to neurodegenerative diseases, epilepsy, inflammatory bowel disease, inflammation, pain and cancer. Research is carried out on epilepsy, brain tumours, Parkinson’s disease, AD, chronic traumatic encephalopathy and Huntington’s disease.

“Cannabinoids like this will revolutionize treatment, prevention and pain in neurology,” she said.

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