New drug being tested in Louisville gives hope to breast cancer patients

In 2017, Andrea Solomon’s life changed dramatically when she was diagnosed with stage 4 breast cancer. “My whole world kind of shut down,” Solomon said. At the end of the year, she started chemotherapy. “After taking certain drugs for a while, the cancer would come back in other areas, and we would basically have to change things up and see what else works,” Solomon said. Solomon says things changed when She started a clinical trial with the Norton Cancer Institute. Solomon says that since then her scan results show that the cancer is not spreading. The drug Enhurtu works by targeting the HER2 gene that causes aggressive breast cancer. Dr Hargis says there’s a reason the treatment is so effective. “The idea here is that they got the small molecules from the chemotherapy. They attach it to the protein antibody. The antibody Searches the body, finds the HER2 protein, stays away from other organs and attaches to it, internalizes it and releases the cancer drug inside the cell,” Hargis said. drug shrank tumors in 61% of patients and tumors disappeared in 6% of patients. The drug also stopped cancer growth for about 16 months. The drug may be able to help even more patients than doctors initially thought. Norton is participating in a drug trial to see if the drug is effective in treating different types of breast cancer. “What this study showed is that this drug is also effective now in about 30 or 40 percent of all breast cancers, which is the huge event,” Hargis said. The drug has been approved by the United States Food and Drug Administration.

In 2017, Andrea Solomon’s life changed dramatically when she was diagnosed with stage 4 breast cancer.

“My whole world kind of stopped,” Solomon said.

At the end of the year, she started chemotherapy.

“After taking certain medications for a while, the cancer would come back in other areas, and we basically had to switch things up and see what else worked,” Solomon said.

Solomon says things changed when she started a clinical trial with the Norton Cancer Institute. Solomon says that since then his scan results show the cancer is not spreading. The drug Enhurtu works by targeting the HER2 gene that causes aggressive breast cancer. Dr Hargis says there is a reason the treatment is so effective.

“The idea here is that they got the small molecules from the chemotherapy. They attach it to the protein antibody. The antibody scavenges the body, finds the HER2 protein, stays away from other organs and s “fixes there. It internalizes it and releases the anti-cancer drug inside the cell,” Hargis said.

In one trial, the drug shrank tumors in 61% of patients and tumors disappeared in 6% of patients. The drug also prevented the cancer from growing for about 16 months.

The drug may be able to help even more patients than doctors initially thought. Norton is participating in a drug trial to see if the drug is effective in treating different types of breast cancer.

“What this study showed is that this drug is also effective now in about 30 or 40 percent of all breast cancers, which is the most important event,” Hargis said.

The drug has been approved by the United States Food and Drug Administration.

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