Covid raises brain disorders and epilepsy risks in children months later

Not only adults, children who have suffered from Covid-19 are also at increased risk of cognitive impairment, insomnia, ischemic stroke, nervous/psychotic disorders and epilepsy or seizures even months later. have been infected, a large-scale observational study of more than 1.25 million patient health records found.

According to the journal The Lancet Psychiatry, the study which looked at data from 185,748 children found that post-Covid risk trajectories differed in children compared to adults.

During the six months following SARS-CoV-2 infection, children were not at increased risk for mood or anxiety disorders.

However, they had “an increased risk of cognitive impairment, insomnia, intracranial hemorrhage, ischemic stroke, nerve, nerve root and plexus disorders, psychotic disorders, and epilepsy or seizures. “.

Unlike adults, cognitive impairment in children had a finite risk horizon (75 days) and a finite time to reach equal incidence (491 days).

“Children have a milder overall psychiatric risk profile than adults and the elderly, but their higher and sustained risk of certain diagnoses is of concern,” the study said.

A significant proportion of older adults with a neurological or psychiatric diagnosis, in either cohort, subsequently died, particularly those diagnosed with dementia, epilepsy, or seizures.

Immediately after the emergence of the delta variant, increased risks of ischemic stroke, epilepsy or seizures, cognitive impairment, insomnia and anxiety disorders were observed, compounded by an increased mortality rate .

“With Omicron, the mortality rate was lower than just before the emergence of the variant, but the risks of neurological and psychiatric outcomes remained similar,” found the study, led by researchers from the University of ‘Oxford UK.

The observational study extracted data from the “TriNetX” electronic health record network, an international network of anonymized data from the health records of approximately 89 million patients collected from hospitals, primary care providers and specialists (mainly from the United States, but also from Australia, the United Kingdom, Spain, Bulgaria, India, Malaysia and Taiwan).

“This analysis of 2-year retrospective cohort studies of individuals diagnosed with Covid-19 showed that the increased incidence of mood and anxiety disorders was transient, with no overall excess of these diagnoses. compared to other respiratory infections,” the researchers noted.

In contrast, the increased risk of psychotic disorder, cognitive impairment, dementia, and epilepsy or seizures persisted throughout the study.

“The fact that neurological and psychiatric outcomes were similar during Delta and Omicron waves indicates that the burden on the healthcare system may continue even with less severe variants in other respects,” the researchers warned.

About Michael Bill

Check Also

Reverse Dravet Restoration of SCN1A Gene Activity in a Mouse Model | Seizures stopped, further gains seen even after symptom onset

Restoring the activity of Scn1a – a murine variant of the gene that is often …