Treat Seizure – Kepplah http://kepplah.com/ Tue, 22 Nov 2022 03:32:26 +0000 en-US hourly 1 https://wordpress.org/?v=5.9.3 https://kepplah.com/wp-content/uploads/2021/05/kepplah-150x150.png Treat Seizure – Kepplah http://kepplah.com/ 32 32 Maryland Governor recognizes NEAM with purple lights https://kepplah.com/maryland-governor-recognizes-neam-with-purple-lights/ Tue, 22 Nov 2022 03:32:26 +0000 https://kepplah.com/maryland-governor-recognizes-neam-with-purple-lights/

Bowie, Maryland, November 22, 2022 – Today, Governor Larry Hogan will light up the Governor’s House in purple not only to mark National Epilepsy Awareness Month, but also to celebrate the passing of Brynleigh Act (Senate Bill 299) and Bill’s namesake, Brynleigh Shillinger. Brynleigh, who suffers from epilepsy and a rare genetic condition called tuberous sclerosis complex (TSC), turned 9 on the same day. Maryland became the 15th state in the nation to pass safe schools legislation in April 2022. The passage of this bill is of particular significance to the Epilepsy Foundation, headquartered in Maryland, and its success follows similar legislation passed in other states.

“Earlier this year, I had the honor of signing legislation, also known as Brynleigh Act— which increases the number of staff in Maryland public schools needed to undergo professional training in crisis reconnaissance and response,” Governor Hogan said. “Our administration is proud to support epilepsy awareness efforts and advocate on behalf of tens of thousands of Marylanders across our state living with epilepsy.”

Nearly 60,000 Marylanders live with active epilepsy, including nearly 8,000 children and adolescents. Epilepsy affects everyone. Anyone can have a seizure and be diagnosed with epilepsy. During their lifetime, 1 in 10 people will have a seizure and 1 in 26 will develop epilepsy. The Epilepsy Foundation strives to educate the public and advocate for those we know and those we don’t yet know who are living with seizures.

About epilepsy

According to the World Health Organization, epilepsy is the most common serious brain disorder in the world, regardless of age, race, social class, nationality or geography. The United States Centers for Disease Control & Prevention (CDC) estimates that 3.4 million people in the United States are affected by epilepsy. Epilepsy is the underlying tendency of the brain to produce seizures which are sudden, abnormal bursts of electrical energy that disrupt brain function.

About the Epilepsy Foundation

With a network of partners across the United States, The Epilepsy Foundation connects people to treatment, support and resources; leads advocacy efforts; funds innovative research and the training of specialists; and educates the public about epilepsy and seizure first aid. In partnership with the CDC, the Epilepsy Foundation has helped improve access to care for people with epilepsy, expand its digital reach and online resources into homes across the country, and train people to seizure recognition and first aid. To learn more, visit epilepsy.com or call 1.800.332.1000.

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COVID-19 increases the risk of seizures and epilepsy https://kepplah.com/covid-19-increases-the-risk-of-seizures-and-epilepsy/ Sat, 19 Nov 2022 07:16:56 +0000 https://kepplah.com/covid-19-increases-the-risk-of-seizures-and-epilepsy/

November 18, 2022 – Nearly one in 100 people infected with COVID-19 developed epilepsy or seizures within 6 months of becoming ill, according to a new study.

The risk is highest in children and in those who have not been hospitalized for treatment for COVID-19.

“Although the overall risk of developing seizures or epilepsy is low – less than 1% of all people with COVID-19, given the large number of people who have been infected with COVID-19, this could lead to an increase in the number of people with seizures and epilepsy,” said study author Arjune Sen, MD, PhD, in a Press release. “Additionally, the increased risk of seizures and epilepsy in children gives us another reason to try to prevent COVID-19 infections in children.”

Published this week in the magazine Neurology, the study assessed two groups – those infected with COVID-19 and those infected with influenza. Each group had 152,754 people who were followed for 6 months.

Those in the COVID-19 group were 55% more likely to develop epilepsy or seizures during this time, compared to those in the flu group. For the COVID-19 group, the incidence of epilepsy or seizures was 0.94%, compared to 0.60% for patients with influenza. In children, the incidence was 1.34% in COVID-19 patients and 0.69% in influenza patients.

The higher rate of epilepsy and seizures in patients with relatively mild symptoms, compared to those who were hospitalized with COVID-19, was also of concern, Wyatt Bensken, PhD, and Terence J. O’Brien wrote. , MD, in a comment published alongside the study. They also said healthcare providers who treat brain and nervous system disorders need to be prepared for an increase in patient numbers. Indeed, even if the risk of seizures or epilepsy is low, the large number of people infected with COVID-19 could mean a large increase in the number of people who develop epilepsy or seizures.

One theory for the findings is that COVID-19 may cause problems with brain function by affecting brain cells “that make up the lining of blood vessels or by causing inflammation, immune overreaction, or other mechanisms,” according to one. summary of the study published by the Center for Infectious Disease Research and Policy.

The study authors said their research was limited by not knowing which variants of COVID-19 infect patients.

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Priest and teenager walk away unscathed after freak accident in Milford: ‘A real miracle’ https://kepplah.com/priest-and-teenager-walk-away-unscathed-after-freak-accident-in-milford-a-real-miracle/ Tue, 15 Nov 2022 03:28:00 +0000 https://kepplah.com/priest-and-teenager-walk-away-unscathed-after-freak-accident-in-milford-a-real-miracle/

MILFORD, Ohio (WXIX) – A teenager has miraculously walked away from an accident at a church in Milford where his car drove over a priest.

Brandon Varner, 17, was the driver around 9 a.m. on the first Sunday in October. His SUV drove through a yard, slammed into a concrete picnic table, then flew away.

Candy Varner, Brandon’s mother, says her son left early that morning to teach Sunday school at St. Andrew the Apostle Catholic Church, just three minutes from their home.

“For us, we just got the knock on the door that no one ever wants to have,” she recalls. “An officer stopped to let us know that our son had been involved in an accident.”

EMS transported Brandon to Cincinnati Children’s Hospital Medical Center, but he escaped without even a scratch.

He says he doesn’t remember anything.

“I don’t remember anything except leaving the house and driving down the street, then I had the seizure, and I passed out completely and I don’t remember anything from there,” he said.

Brandon didn’t learn what had happened until the hospital, where he was shown the surveillance video.

“I was mostly stunned by it. I didn’t think much about it. I was just shocked to hear what happened,” he said.

Brandon says he’s never had a seizure before. He is still in disbelief that no one was hurt.

“A real miracle,” he says. “I ended up with just a little scratch on my hand, and nothing happened to Father [John] Bouk.

The family says Brandon is fine and being treated for epilepsy.

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Psychedelic treatment: Woman writes heartbreaking letter to PM https://kepplah.com/psychedelic-treatment-woman-writes-heartbreaking-letter-to-pm/ Sat, 12 Nov 2022 15:48:51 +0000 https://kepplah.com/psychedelic-treatment-woman-writes-heartbreaking-letter-to-pm/

A heartbroken woman has sent a letter to Anthony Albanese pleading with the government to take further action to legalize alternative treatments for depression after her husband took his own life.

The woman, who only used Vanessa’s name, said her husband Franco had exhausted the list of drugs available to treat depression in Australia – to no avail.

In the 23-page letter, she listed all the treatments and their effects on her husband for more than 30 years, revealing that he reacted negatively to most.

In her rush to find solutions, Vanessa got in touch with Mind Medicine Australia, an organization that advocates for the approval of psychedelics for use as a treatment for depression, as used in several overseas countries. sea.

Unfortunately, with the regulations in force in Australia, there is no legal route to access these treatments.

She described the pain of living next to her husband going through a debilitating depression, detailing several side effects he experienced with Therapeutic Goods Administration (TGA)-approved drugs.

Side effects of these drugs included severe headaches, memory loss and bowel problems, with some drugs allegedly increasing his suicidal thoughts instead of stopping them.

“He suffered so deeply, for so long, until we finally reached the point of exhausting all the options the Australian medical system had to offer,” she wrote to Mr Albanese.

“Anthony, if that doesn’t highlight the absurd cruelty of the TGA’s current stance on psychedelic drugs, then frankly, I don’t know what will.

“In what world is it right to deny treatment-resistant Australians access to these potentially life-saving drugs on the pretext of ‘protecting’ them.”

She said her husband had taken a course in electrical convulsive therapy (ECT), “a process by which electricity is passed through your brain to induce a seizure to treat mental illness”.

She said Franco was hospitalized seven more times over the next three years where he received a “staggering 96” ECT, 24 transcranial magnetic stimulations and prescribed 19 different antidepressants and antipsychotics.

Patients undergoing psychedelic therapy have reported positive results overseas, with some making “significant” progress in just two to three sessions.

On October 21, 2022, the TGA again denied access to psychedelic drugs, citing insufficient evidence to justify their use.

Read Vanessa’s full letter to the Prime Minister here

Vanessa asked Mr Albanese – her local member in Sydney’s central west – to meet with her to discuss the current drug programming and to find a way to enable treatment-resistant patients to access the treatments used in the whole world.

This is in response to the TGA’s recent interim decision not to support the limited postponement of psilocybin, a compound found in “magic mushrooms” which can induce degrees of euphoria, and MDMA which is the drug of ecstasy and can increase mood.

If successful, the postponement will allow patients with treatment-resistant depression, like Franco, to access psychedelic-assisted therapy in a medical setting under the strict controls outlined in the postponement requests.

If approved, Australia will be in line with other countries, including Canada, Switzerland and Israel, in allowing access to these treatments through compassionate and expanded access schemes.

There has been progress on the issue in recent days abroad, notably in the United States.

On November 11, the state of Colorado became the second US state after Oregon to legalize facilitated psilocybin services.

“The legislation opens the door to treatments with other psychedelics and decriminalizes the personal use and possession of most entheogens,” researcher Dennis McKenna tweeted Friday.

The TGA’s final decision will be announced in December, with a public submission period currently open until November 24.

Read related topics:Anthony Albanian
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Treatment of symptoms and all about the brain disorder that Fatima Sana Shaikh talks about https://kepplah.com/treatment-of-symptoms-and-all-about-the-brain-disorder-that-fatima-sana-shaikh-talks-about/ Fri, 04 Nov 2022 09:14:59 +0000 https://kepplah.com/treatment-of-symptoms-and-all-about-the-brain-disorder-that-fatima-sana-shaikh-talks-about/

Fatima Sana Shaikh is raising awareness with her latest article on a neurological condition called epilepsy. Know what this brain disorder is, its symptoms, treatment and much more.

Epilepsy: symptoms, treatment and all about the brain disorder Fatima Sana Shaikh talks about (Source: Freepik)

Fatima Sana Shaikh is currently creating a lot of buzz on the internet after posting an awareness message regarding epilepsy, a brain disorder that causes recurrent and unprovoked seizures due to disturbed activity of nerve cells living in the brain. With her post, the actress marks the 2022 Epilepsy Awareness Challenge. She shared a mirror selfie and wore a fuzzy trench coat, on her social media, while writing a caption about epilepsy that appeals to the big audience as she also urged people to share their epilepsy stories. The caption reads: “I just wanted to post a photo to talk about epilepsy. Koi relevance nahi hai photo about ka 😂

What is epilepsy?

Epilepsy is a brain disorder that causes recurrent unprovoked seizures due to disturbed activity of nerve cells living in the brain. You are often diagnosed with epilepsy if you have two or more unprovoked seizures. Epilepsy can occur as a result of a genetic disease or brain injury, but many people never know the cause.

Fatima Sana Shaikh also added five facts about epilepsy that people need to know, 1. 1 in 26 people will develop epilepsy, 2. There are four main types of epilepsy (focal onset, secondary generalized onset, combination and unknown) 3. Estimates are about 1/3 of people with epilepsy have drug-resistant (ie refractory or incurable) epilepsy. 4. Anything someone can do while conscious can be done during a seizure with altered consciousness (walking, talking, eating,) 5. Almost anything can be a seizure trigger for someone.

Check out the job:

Epilepsy:

It is a neurological disorder characterized by recurrent unprovoked seizures. A seizure is an abnormal increase in electrical activity in your brain. Epilepsy is diagnosed when you have two or more seizures with no other identifiable cause.

Signs and symptoms of epilepsy:

  1. Temporary confusion
  2. Looking at
  3. Stiff muscles
  4. Uncontrollable jerky movements of the arms and legs
  5. Loss of consciousness or consciousness
  6. Psychological symptoms such as fear, anxiety or deja vu
  7. sleep disorders
  8. panic attacks
  9. Nightmares
  10. Fainting
  11. Particular changes in the senses, such as smell, touch, and sound
  12. Fear for no apparent reason

Treatment:

Currently, there is no cure for most types of epilepsy. A doctor may prescribe antiepileptic drugs (AEDs) to help prevent seizures. If these medications don’t work, other possible options include surgery, vagus nerve stimulation, or a special diet.




Publication date: November 4, 2022 2:44 PM IST



Date Updated: Nov 4, 2022 2:48 PM IST

]]> FDA warns Amazon and Walmart against selling mislabeled drugs — Pain News Network https://kepplah.com/fda-warns-amazon-and-walmart-against-selling-mislabeled-drugs-pain-news-network/ Tue, 01 Nov 2022 22:15:54 +0000 https://kepplah.com/fda-warns-amazon-and-walmart-against-selling-mislabeled-drugs-pain-news-network/

“Failure to adequately address this matter may result in legal action, including, but not limited to, seizure and/or injunction. Please submit a written response to this letter within fifteen business days from the date of receipt, explaining the specific steps you have taken to remedy any violation,” the FDA letter reads.

Similar warning letters were sent to Walmart and Latin Foods Market, which had previously issued voluntary recalls for the supplements but continued to sell them.

It appears that the Artri and Ortiga supplements have now been removed from all three companies’ websites. The supplements were marketed primarily to Spanish-speaking consumers, with claims that they are “very effective in restoring cartilage” and “combat arthritis”.

Diclofenac increases the risk of cardiovascular events, such as heart attacks and strokes, as well as serious gastrointestinal bleeding and damage. When used long term or in high doses, dexamethasone and other corticosteroids can cause severe withdrawal symptoms if a user suddenly stops taking them. Both drugs can also interact with other drugs.

The FDA encourages health care providers and patients to report side effects related to product use to its Adverse Event Reporting System. .

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Full Spectrum Brain Stimulation | CBD Project https://kepplah.com/full-spectrum-brain-stimulation-cbd-project/ Wed, 26 Oct 2022 23:36:49 +0000 https://kepplah.com/full-spectrum-brain-stimulation-cbd-project/

In 2013, mainstream media began reporting on the promise of aCBD strains like Charlotte’s Web (named after a five-year-old girl whose grand mal seizures were dramatically reduced with cannabis oil) to treat seemingly intractable epileptic seizures in children. By garnering public support for greater access to medical cannabis among families in need, these stories helped advance the cannabis legalization campaigns that continue to this day.

Although other medical and therapeutic uses of cannabis (such as for pain, nausea and sleep problems) now seem to dominate public discourse, the plant’s ability to improve a variety of neurological disorders remains a topic of interest. significant in health care and scientific research. . Cannabis constituents are being studied for potential use in treating not only epileptic seizures, but also traumatic brain injury, neurodegenerative diseases such as Alzheimer’s, Parkinson’s and Huntingon’s disease, and other neurological disorders.

Project CBD identified four recently published articles on the topic, including two reviews of previous research and two original studies. Together they offer an overview of the state of the science, including what remains to be learned and what is becoming increasingly clear.

Not just cannabinoids

A multitude of cannabis-derived phytochemicals, including cannabinoids, terpenes, flavonoids and other antioxidants, have shown neuroprotective effects through various cellular and molecular pathways in preclinical research, according to researchers from the University of Adelaide. Scott Smid and John Staton Laws III in a new review of the journal Phytomedicine.1

Cannabis-sativa synthesizes many classes of secondary metabolites including more than 140 terpenes, 104 cannabinoids, [and] 26 flavonoids… which demonstrate a diverse range of bioactivities,” the authors write. Of these, a surprising number have been shown in previous studies to possess neuroprotective properties, including cannabinoids CBD, Radio Canada [cannabichromene]Delta-8 THCand Delta-9 THC; the terpenes limonene, myrcene, linalool, alpha-pinene, beta-caryophyllene, humulene, alpha-bisabolol, friedelin and terpinolene; and the flavonoid cannflavin A.

Although these findings in cells and animal models have not been confirmed in randomized, controlled clinical studies in humans, they nevertheless provide “strong evidence” for a role for the constituents of cannabis, individually or in combination. , as potential neuroprotectors, write the authors – and lend support to the idea of ​​using medical cannabis as a treatment for Alzheimer’s disease and other neurodegenerative diseases.

Spotlight on CBD

A second recent review, published in the journal Molecules in August,2 emphasizes the ability to CBD and certain synthetic derivatives for reducing neuroinflammation mediated by microglia, central nervous system immune cells known to be modulated by the endocannabinoid system.3 Since many common neurological disorders are characterized by inflammation of the brain, cannabinoids could potentially support disease prevention and/or treatment by tempering or reversing the pro-inflammatory response of microglia.

A growing body of clinical and preclinical evidence supports this hypothesis, write the authors, also based in Australia (in this case, Western Sydney University) – especially for cannabidiol. “CBD has promising therapeutic effects… [for] neurological disorders such as epilepsy, multiple sclerosis, ischemic brain damage, neuropathic pain, schizophrenia and Alzheimer’s disease,” they note. “A number of preclinical studies suggest that CBD exhibited potent inhibitory effects of neurotoxic molecules and inflammatory modulators, highlighting its remarkable therapeutic potential for the treatment of numerous neurological disorders.

However, they add, the molecular mechanisms of action that underlie CBDThe effects of on neuroinflammation via microglia appear to be complex and are still poorly understood. To shed light on the matter, the authors review what current science says about several pathways thought to be crucial to the pathophysiology of microglia-mediated neuroinflammation, including – alphabet soup alert! – “the downward regulation of NADPH mediated by oxidase SAR, TLR4NCκB, and NFI-β-J.A.K.STAT ways. »

Finally, the authors summarize preclinical studies investigating the anti-neuroinflammatory activity of more potent synthetic substances. CBD derivatives, and CBD in tandem with THC. All told – despite the uncertainties about the precise mechanisms – the evidence looks pretty good, they conclude.

More support for full-spectrum extracts

Meanwhile, recent articles from Italy and Spain describe studies using in vitro (in cells) tests to further assess the neuroprotective potential of various cannabis constituents.

The first, published in September in Frontiers in pharmacology,4 evaluated the antioxidant and neuroprotective activity in mouse brain cells of two extracts – one in water and the other in hexane – of the “industrial hemp” strain Futura 75. While this strain is said to contain 2- 3% CBD and about 0.1% THCthe authors note that they are interested not only in cannabinoids, but also in terpenes, alkaloids and especially flavonoids.

The extracts showed an array of “striking” and “interesting” effects, the authors conclude, and “could be a source of compounds potentially beneficial to human health, particularly related to neurodegenerative disorders.”

The second article, recently published online and which appeared in the November issue of Fitoterapia,5 tests a different full-spectrum cannabis extract on a different cell line using different assays suggesting neuroprotective effects. But again, the work “demonstrates[s] the in vitro Efficiency of Cannabis-sativa extract as a neuroprotective agent,” the authors write, “providing the entire cannabis phytocomplex as a more effective strategy, compared to its main constituents alone.


Nate Seltenrich, a freelance science journalist based in the San Francisco Bay Area, covers a wide range of topics, including environmental health, neuroscience, and pharmacology. Copyright, Project CBD. May not be reprinted without permission.


Sources

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Toxic Dog Foods: Dr. Katrina Warren on Halloween Trick or Treat Dangers for Dogs and Puppies https://kepplah.com/toxic-dog-foods-dr-katrina-warren-on-halloween-trick-or-treat-dangers-for-dogs-and-puppies/ Mon, 24 Oct 2022 04:14:36 +0000 https://kepplah.com/toxic-dog-foods-dr-katrina-warren-on-halloween-trick-or-treat-dangers-for-dogs-and-puppies/

This is howl-oween!

As families prepare to celebrate the culmination of spooky season with a trick or treat – a activity that has gained popularity in Australia – there are some things families with fur babies need to keep in mind.

With toddlers (and, let’s be real, parents too) indulging in chocolate and other treats to commemorate the ancient Celtic holiday, it’s important to make sure these sweets around the house and of the streets do not end up in the mouths of puppies and dogs.

Young children can’t be trusted to keep their Halloween stash out of reach of pets, and often leave half-eaten chocolate and candy lying around, so parents need to be diligent — and here’s why.

READ MORE: Victorian mum talks about her brush with death

Dr. Katrina Warren has a warning for parents who cheat on or deal with children and pets. (Getty)

Don’t underestimate the dangers of chocolate for dogs

Chocolate is very tasty for dogs, but it can be deadly – a small amount of chocolate can put a small dog’s life in danger.

Chocolate contains theobromine, a chemical also known as xantheosis which negatively affects the heart, lungs, kidneys and central nervous system. Generally, the darker the chocolate, the more dangerous it is.

Symptoms of chocolate poisoning include restlessness, hyperactivity, increased thirst, increased urination, gasping, and seizures. If you suspect your pet has consumed chocolate or notice these symptoms, please contact your veterinarian immediately for advice.

LEARN MORE:Wildlife warning with decorations ahead of Halloween

Halloween dogs

Animals in Halloween costumes

READ MORE: Prince William will support the dumping of outdated coronation traditions

The sugar-free sweetener is also not safe for dogs

Xylitol is a common sugar-free sweetener often found in confections like gummies, mints, and other lollipops.

It is becoming more and more popular but, although safe for humans, it is very dangerous for dogs. When dogs consume xylitol, it is very quickly absorbed into the bloodstream, resulting in a powerful release of insulin that can cause blood sugar levels to drop rapidly. It can be life-threatening if not treated quickly.

If you think your dog ate something without sugar, check the ingredient list for xylitol, then call your vet if he ate it.

READ MORE: Flight test of a woman after a cosmetic procedure

Puppy eating a Halloween trick or containing a treat
Packaging is as dangerous to puppies and dogs as food. (Getty)

Beware of food packaging as much as the food itself

Dogs often consume chocolate and confectionery and gobble up the wrappers at the same time.

Eating foil and cellophane wraps can cause choking or bowel obstruction, which may require surgery. Signs include vomiting, loss of appetite, straining to defecate.

If you notice these symptoms in your dog, contact your veterinarian immediately for advice.

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Extreme Halloween: parents who do everything to celebrate

]]> More Americans Smuggle Fentanyl Into US, Politicians Blame Migrants https://kepplah.com/more-americans-smuggle-fentanyl-into-us-politicians-blame-migrants/ Fri, 21 Oct 2022 02:14:56 +0000 https://kepplah.com/more-americans-smuggle-fentanyl-into-us-politicians-blame-migrants/

Fentanyl smuggling is funded by US consumers, and drug cartels continue to hijack US citizens and hire US citizens to smuggle drugs across the border, according to research by the CATO Institute.

“We tried that with heroin, we tried that with marijuana and nothing changed,” said David Bier of the CATO Institute. “Ultimately, the solution to the drug policy problem in the United States will not come through greater border enforcement.”

More Americans Smuggle Fentanyl Into US, Politicians Blame Migrants

In 2021, US citizens made up 86.3% of convicted fentanyl drug traffickers. The study shows that drugs pass through ports of entry and smugglers are 97% less likely to be caught than people crossing illegally between them.

Bier says the demand for the drug is now so high and doesn’t think laws and enforcement in the United States make a difference.

“No one is willing to focus on solutions trying to get these people off the streets and into institutions, where they can manage their pain in an effective way that is not about addiction or reaching out to dangerous criminals to get treatment,” Bière said.

In Depth: 6 Months Pregnant Texas Woman Killed by Fentanyl Overdose

Governor Greg Abbott issued an executive order designating Mexican drug cartels as terrorist organizations and requiring the Texas Department of Public Safety (DPS) to take action.

“Fentanyl is a covert killer, and Texans are being victimized by the Mexican cartels that produce it,” Governor Abbott said. « cartels
are terrorists, and it is time we treated them that way. In fact, more Americans have died from fentanyl poisoning in the past year than all terrorist attacks across the world in the past 100 years. In order to save our country, especially our next generation, we need to do more to get fentanyl off our streets.

The governor also sent a letter to President Joe Biden and Vice President Kamala Harris requesting federal terrorist classifications for the Sinaloa Cartel and the Jalisco Next Generation Cartel, as well as other cartels producing and distributing deadly fentanyl.

Governor Abbott is proposing legislation that would call fentanyl overdoses a balance so they could bring murder charges against those who distribute the drug.

(AP Photo/Yerania Rolon)

Neighbors pray for brothers Yovani and Jair Valencia Olivares and their cousin Misael Olivares in San Marcos Atexquilapan, state of Veracruz, Mexico, Thursday, June 30, 2022. The three youngsters are missing after it was confirmed to the family that They were traveling in the abandoned trailer in San Antonio, Texas, where more than 50 bodies were found.

The DPS claims to have seized more than 336 million “lethal doses” of fentanyl during Operation Lone Star.

David Beir thinks Fentanyl smuggling isn’t a reason to end the asylum. Only 279 out of 1.8 million
illegal crossing Border Patrol arrests resulted in a seizure of fentanyl.

“The only appropriate response to the opioid epidemic is addiction treatment,” the CATO study says. “But for that to happen, the government must adopt policies that facilitate treatment and reduce the harms of addiction, especially deaths. To develop these policies, policymakers must ignore calls to blame strangers for our problems.”

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Angiotensin receptor blocker therapy associated with decreased incidence of epilepsy https://kepplah.com/angiotensin-receptor-blocker-therapy-associated-with-decreased-incidence-of-epilepsy/ Tue, 18 Oct 2022 15:51:13 +0000 https://kepplah.com/angiotensin-receptor-blocker-therapy-associated-with-decreased-incidence-of-epilepsy/ Subscribe We have not been able to process your request. Please try again later. If you …]]>

October 18, 2022

1 minute read


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Researchers have reported in JAMA Neurology.

High blood pressure is associated with an increased incidence of epilepsy, but recent study results suggest that treatment with angiotensin receptor blockers (ARBs) may inhibit epileptic seizures, Corinna Doege, MD, from the Department of Pediatric Neurology at Bremen Central Hospital in Germany, and colleagues reported.

Source: Adobe Stock.

Doege and colleagues sought to assess whether ARB treatment was associated with a decreased incidence of epilepsy in adults with hypertension.

The researchers obtained data from the Disease Analyzer database on patients aged 18 and older with high blood pressure who had at least one prescription for antihypertensive medication. Of more than 1.5 million patients for whom data are available, 168,612 were included in the study (51.4% women; mean age, 62.3 years).

Patients treated with one of four antihypertensive drugs – ARBs, beta-blockers, angiotensin-converting enzyme inhibitors and calcium channel blockers – were matched using propensity scores, with 42,153 patients in each class of drugs. The researchers compared the incidence of epilepsy associated with ARA therapy with the other drugs.

Over 5 years, the incidence of epilepsy was lowest in those treated with ARBs (0.27% at 1 year; 0.63% at 3 years; 0.99% at 5 years) and highest among those receiving beta-blockers (0.38%, 0.91% and 1.47%). %, respectively) and calcium channel blockers (0.38%, 0.93% and 1.48%, respectively).

Compared to other drug classes, treatment with ARBs was associated with a significant decrease in the incidence of epilepsy (HR=0.77; 95% CI, 0.65-0.9).

“The results suggest that antihypertensive drugs could be used as a novel approach to prevent epilepsy in patients with high blood pressure,” the authors wrote.

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